This year, the Schüller group was represented by five scientists at the most important international meeting on neuro-oncology. After cancelling in 2020, the latest research results could be presented and discussed in presence again. Prominent topics of the meeting were developments in immunooncology, single cell sequencing and cancer neuroscience. The trip was partly supported by the Fördergemeinschaft Kinderkrebs-Zentrum Hamburg. Ulrich Schüller and his team presented their research projects on medulloblastoma, glioblastoma, and ependymoma (all meeting papers at https://academic.oup.com/neuro-oncology/issue/23/Supplement_6#1302913-6426833) and aim to further collaborate with other research groups around the world.